QT interval variations and mortality risk: Is there any relationship? (2024)

1. Priori SG, Schwartz PJ, Napolitano C, Bloise R, Ronchetti E, Grillo M, et al. Risk stratification in the long-QT syndrome. N Engl J Med. 2003;348:1866–74. [CrossRef] [PubMed] [Google Scholar]

2. Gaita F, Giustetto C, Bianchi F, Wolpert C, Schimpf R, Riccardi R, et al. Short QT Syndrome: a familial cause of sudden death. Circulation. 2003;108:965–70. [CrossRef] [PubMed] [Google Scholar]

3. Gallagher MM, Magliano G, Yap YG, Padula M, Morgia V, Postorino C, et al. Distribution and prognostic significance of QT intervals in the lowest half centile in 12,012 apparently healthy persons. Am J Cardiol. 2006;98:933–5. [CrossRef] [PubMed] [Google Scholar]

4. Mason JW, Ramseth DJ, Chanter DO, Moon TE, Goodman DB, Mendzelevski B, et al. Electrocardiographic reference ranges derived from 79,743 ambulatory subjects. J Electrocardiol. 2007;40:228–34. [CrossRef] [PubMed] [Google Scholar]

5. Funada A, Hayashi K, Ino H, Fujino N, Uchiyama K, Sakata K, et al. Assessment of QT intervals and prevalence of short QT syndrome in Japan. Clin Cardiol. 2008;31:270–4. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

6. Kobza R, Roos M, Niggli B, Abacherli R, Lupi GA, Frey F, et al. Prevalence of long and short QT in a young population of 41,767 predominantly male Swiss conscripts. Heart Rhythm. 2009;6:652–7. [CrossRef] [PubMed] [Google Scholar]

7. Zhang Y, Post WS, Blasco-Colmenares E, Dalal D, Tomaselli GF, Guallar E. Electrocardiographic QT interval and mortality: a metaanalysis. Epidemiology. 2011;22:660–70. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

8. Priori SG, Wilde AA, Horie M, Cho Y, Behr ER, Berul C, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm. 2013;10:1932–63. [CrossRef] [PubMed] [Google Scholar]

9. Garg A, Lehmann MH. Prolonged QT interval diagnosis suppression by a widely used computerized ECG analysis system. Circ Arrhythm Electrophysiol. 2013;6:76–83. [CrossRef] [PubMed] [Google Scholar]

10. Rautaharju PM, Surawicz B, Gettes LS. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Davey P QT interval and mortality from coronary artery disease. Prog Cardiovasc Dis. 2000;119:940–51. [PubMed] [Google Scholar]

11. Luo S, Michler K, Johnston P, Macfarlane PW. A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs. J Electrocardiol. 2004;37:81–90. [CrossRef] [PubMed] [Google Scholar]

12. Roden DM. Long QT syndrome: reduced repolarization reserve and the genetic link. J Intern Med. 2006;259:59–69. [CrossRef] [PubMed] [Google Scholar]

13. Extramiana F, Antzelevitch C. Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome. Circulation. 2004;110:3661–6. [CrossRef] [PubMed] [Google Scholar]

14. Vrtovec B, Knezevic I, Poglajen G, Sebestjen M, Okrajsek R, Haddad F. Relation of B-type natriuretic peptide level in heart failure to sudden cardiac death in patients with and without QT interval prolongation. Am J Cardiol. 2013;111:886–90. [CrossRef] [PubMed] [Google Scholar]

15. Lee JM, Janardhan AH, Kang KW, Joung B, Pak HN, Sundaram S, et al. Paced QT interval is a better predictor of mortality than the intrinsic QT interval: Long-term follow-up study. Heart Rhythm. 2014;11:1184–9. [CrossRef] [PubMed] [Google Scholar]

16. Panoulas VF, Toms TE, Douglas KM, Sandoo A, Metsios GS, Stavropoulos-Kalinoglou A, et al. Prolonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden. Rheumatology (Oxford) 2014;53:131–7. [CrossRef] [PubMed] [Google Scholar]

17. Genovesi S, Rossi E, Nava M, Riva H, De Franceschi S, Fabbrini P, et al. A case series of chronic haemodialysis patients: mortality, sudden death, and QT interval. Europace. 2013;15:1025–33. [CrossRef] [PubMed] [Google Scholar]

18. Upadhya B, Ntim W, Brandon Stacey R, Henderson R, Leedy D, O’Brien FX, et al. Prolongation of QTc intervals and risk of death among patients with sickle cell disease. Eur J Haematol. 2013;91:170–8. [CrossRef] [PubMed] [Google Scholar]

19. Farsi D, Mirafzal A, Hassanian-Moghaddam H, Azizi Z, Jamshidnejad N, Zehtabchi S. The correlation between prolonged corrected QT interval with the frequency of respiratory arrest, endotracheal intubation, and mortality in acute methadone overdose. Cardiovasc Toxicol. 2014;14:358–67. [CrossRef] [PubMed] [Google Scholar]

20. Kobza R, Roos M, Niggli B, Abacherli R, Lupi GA, Frey F, et al. Prevalence of long and short QT in a young population of 41,767 predominantly male Swiss conscripts. Heart Rhythm. 2009;6:652–7. [CrossRef] [PubMed] [Google Scholar]

21. Moriya M, Seto S, Yano K, Akahoshi M. Two cases of short QT interval. Pacing Clin Electrophysiol. 2007;30:1522–6. [CrossRef] [PubMed] [Google Scholar]

22. Antzelevitch C, Pollevick GD, Cordeiro JM, Casis O, Sanguinetti MC, Aizawa Y, et al. Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST segment elevation, short QT intervals, and sudden cardiac death. Circulation. 2007;115:442–9. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

23. Gu Q, Burt VL, Paulose-Ram R, Yoon S, Gillum RF. High blood pressure and cardiovascular disease mortality risk, among U.S. adults: the third National Health and Nutrition Examination Survey mortality follow-up study. Ann Epidemiol. 2008;18:302–9. [CrossRef] [PubMed] [Google Scholar]

24. Davey P QT. interval and mortality from coronary artery disease. Prog Cardiovasc Dis. 2000;42:359–84. [CrossRef] [PubMed] [Google Scholar]

25. Moss AJ. QTc prolongation and sudden cardiac death: the association is in the detail. J Am Coll Cardiol. 2006;47:368–9. [CrossRef] [PubMed] [Google Scholar]

26. Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, et al. Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. Circulation. 2009;119:240–51. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

27. Algra A, Tijssen JG, Roelandt JR, Pool J, Lubsen J. QT interval variables from 24 hour electrocardiography and the two year risk of sudden death. Br Heart J. 1993;70:43–8. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

28. Anttonen O, Junttila MJ, Rissanen H, Reunanen A, Viitasalo M, Huikuri HV, et al. Prevalence and prognostic significance of short QT interval in a middle-aged Finnish population. Circulation. 2007;116:714–20. [CrossRef] [PubMed] [Google Scholar]

29. Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, et al. Genetic variations in NOS1AP are associated with sudden cardiac death in US white community-based populations. Circulation. 2009;119:940–51. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

30. Straus SM, Kors JA, De Bruin ML, van der Hooft CS, Hofman A, Heeringa J, et al. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol. 2006;47:362–7. [CrossRef] [PubMed] [Google Scholar]

31. Rautaharju PM, Kooperberg C, Larson JC, LaCroix A. Electrocardiographic abnormalities that predict coronary heart disease events and mortality in postmenopausal women: the Women’s Health Initiative. Circulation. 2006;113:473–80. [CrossRef] [PubMed] [Google Scholar]

32. Sohaib SM, Papacosta O, Morris RW, Macfarlane PW, Whincup PH. Length of the QT interval: determinants and prognostic implications in a population-based prospective study of older men. J Electrocardiol. 2008;41:704–10. [CrossRef] [PubMed] [Google Scholar]

33. Zhang Y, Post WS, Dalal D, Blasco-Colmenares E, Tomaselli GF, Guallar E. QT-interval duration and mortality rate results from the third national health and nutrition examination survey. Arch Intern Med. 2011;171:1727–33. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

34. Nielsen JB, Graff C, Rasmussen PV, Pietersen A, Lind B, Olesen MS, et al. Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population. Eur Heart J. 2014;35:1335–44. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

35. Darpo B, Sarapa N, Garnett C, Benson C, Dota C, Ferber G, et al. The IQ-CSRC prospective clinical phase 1 study: “Can early QT assessment using exposure response analysis replace the thorough QT study”? Ann Noninvasive Electrocardiol. 2014;19:70–81. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

36. Sager PT, Kowey P. The thorough QT study: Is its demise on the horizon? Ann Noninvasive Electrocardiol. 2014;19:1–3. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

37. Fossa AA, Zhou M, Brennan N, Round P, Ford J. Use of continuous ECG for improvements in assessing the standing response as a positive control for QT prolongation. Ann Noninvasive Electrocardiol. 2014;19:82–9. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

38. Nishibe T, Sato K, Yoshino K, Seki R, Yana K, Ono T. RR-QT interval trend covariability for sudden cardiac death risk stratification. Conf Proc IEEE Eng Med Biol Soc. 2012;2012:4287–90. [PubMed] [Google Scholar]

39. Fossa AA, Zhou M. Assessing QT prolongation and electrocardiography restitution using a beat-to-beat method. Cardiology J. 2010;3:230–43. [PubMed] [Google Scholar]

40. Jensen MT, Marott JL, Allin KH, Nordestgaard BG, Jensen GB. Resting heart rate is associated with cardiovascular and all-cause mortality after adjusting for inflammatory markers: the Copenhagen City Heart Study. Eur J Prev Cardiol. 2012;19:102–8. [CrossRef] [PubMed] [Google Scholar]

41. Magnani JW, Gorodeski EZ, Johnson VM, Sullivan LM, Hamburg NM, Benjamin EJ, et al. P wave duration is associated with cardiovascular and all-cause mortality outcomes: the National Health and Nutrition Examination Survey. Heart Rhythm. 2011;8:93–100. [CrossRef] [PMC free article] [PubMed] [Google Scholar]

42. Aro AL, Huikuri HV, Tikkanen JT, Junttila MJ, Rissanen HA, Reunanen A, et al. QRS-T angle as a predictor of sudden cardiac death in a middle-aged general population. Europace. 2012;14:872–6. [CrossRef] [PubMed] [Google Scholar]

43. Choo WK, Turpie D, Milne K, Davidson L, Elof*cke P, Whitfield J, et al. Prescribers’practice of assessing arrhythmia risk with QT-prolonging medications. Cardiovasc Ther. 2014;32:209–13. [CrossRef] [PubMed] [Google Scholar]

44. Katibi I, Clark EN, Devine B, Lloyd SM, Macfarlane PW. Normal limits of the electrocardiogram in Nigerians. J Electrocardiol. 2013;46:289–95. [CrossRef] [PubMed] [Google Scholar]

QT interval variations and mortality risk: Is there any relationship? (2024)

References

Top Articles
Latest Posts
Article information

Author: Rev. Leonie Wyman

Last Updated:

Views: 5863

Rating: 4.9 / 5 (79 voted)

Reviews: 94% of readers found this page helpful

Author information

Name: Rev. Leonie Wyman

Birthday: 1993-07-01

Address: Suite 763 6272 Lang Bypass, New Xochitlport, VT 72704-3308

Phone: +22014484519944

Job: Banking Officer

Hobby: Sailing, Gaming, Basketball, Calligraphy, Mycology, Astronomy, Juggling

Introduction: My name is Rev. Leonie Wyman, I am a colorful, tasty, splendid, fair, witty, gorgeous, splendid person who loves writing and wants to share my knowledge and understanding with you.